Tags: Calmodulin

All Categories (1-6 of 6)

  1. A Multi-state Model of the CaMKII Holoenzyme using MCell 3.3

    2019-07-27 20:25:41 | Datasets | Contributor(s): Matthew C Pharris, Tamara L Kinzer-Ursem | doi:10.4231/MBPK-D277

    This model uses a specialized rule-based syntax in MCell 3.3 to model the twelve-subunit CaMKII holoenzyme without inducing combinatorial explosion. The model allows us to explore the regulation of CaMKII activation and autophosphorylation.

    https://purr.purdue.edu/publications/3138

  2. A Multi-state Model of the CaMKII Holoenzyme using MCell 3.3

    2019-03-07 14:18:02 | Datasets | Contributor(s): Matthew C Pharris, Tamara L Kinzer-Ursem | doi:10.4231/MBPK-D277

    This model uses a specialized rule-based syntax in MCell 3.3 to model the twelve-subunit CaMKII holoenzyme without inducing combinatorial explosion. The model allows us to explore the regulation of CaMKII activation and autophosphorylation.

    https://purr.purdue.edu/publications/3138

  3. Competitive Tuning of Ca2+/Calmodulin-Activated Proteins Provides a Compensatory Mechanism for AMPA Receptor Phosphorylation in Synaptic Plasticity

    2018-07-27 18:46:11 | Datasets | Contributor(s): Matthew C Pharris, Tamara L. Kinzer-Ursem | doi:10.4231/R7ST7N11

    Code for the basic 4-state competitive binding model that builds on previous work by incorporating an additional competitor for calmodulin along with a number of downstream proteins. Also include is sample code for global sensitivity analysis...

    https://purr.purdue.edu/publications/2926

  4. Next Generation Calmodulin Affinity Purification Data

    2018-06-01 00:00:00 | Datasets | Contributor(s): Julia Fraseur, Tamara L Kinzer-Ursem | doi:10.4231/R7Q81B9G

    Coomassie-stained gels used in semi-quantitative analysis of purified calcineurin from calmodulin Sepharose resins.

    https://purr.purdue.edu/publications/2954

  5. Competitive Tuning of Ca2+/Calmodulin-Activated Proteins Provides a Compensatory Mechanism for AMPA Receptor Phosphorylation in Synaptic Plasticity

    2018-02-15 20:47:41 | Datasets | Contributor(s): Matthew C Pharris, Tamara L. Kinzer-Ursem | doi:10.4231/R7ST7N11

    Code for the basic 4-state competitive binding model that builds on previous work by incorporating an additional competitor for calmodulin along with a number of downstream proteins. Also include is sample code for global sensitivity analysis...

    https://purr.purdue.edu/publications/2926

  6. Mathematica Files: Competitive tuning: competition’s role in setting the frequency-dependence of Ca2+-dependent proteins

    2017-09-02 07:19:24 | Datasets | Contributor(s): Daniel Romano, Matthew C Pharris, Neal Patel, Tamara Kinzer-Ursem | doi:10.4231/R7154F7Q

    We study the competition among seven well-studied neuronal proteins for their common binding partner, calmodulin. We find that competition narrows and shifts the range over which proteins can be activated.

    https://purr.purdue.edu/publications/2789

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