Data from: Perfluoroalkyl substances increase susceptibility of northern leopard frog tadpoles to trematode infection

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By Sophia Brown1, Wes Flynn1, Jason Hoverman1

Purdue University

These data correspond to a paper entitled "Perfluoroalkyl substances increase susceptibility of northern leopard frog tadpoles to trematode infection" by Brown et al. published in Environmental Toxicology & Chemistry.

Version 1.0 - published on 13 Feb 2020 doi:10.4231/Q5AE-XK39 - cite this Content may change until committed to the archive on 13 Mar 2020

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Per/polyfluoroalkyl substances (PFAS) are contaminants of emerging concern that can impair immune function, yet few studies have tested whether exposure increases infection risk.  Using laboratory experiments, we found that exposure to 10 ppb of perfluorohexanesulfonic acid increased trematode (Echinoparyphiumlineage 3) infectionsin larval northern leopard frogs (Lithobates pipiens). However, there was no effect of perfluorooctanesulfonic acid. Our results demonstrate that PFAS can potentially enhance infection risk in natural systems. 

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