A Multi-state Model of the CaMKII Holoenzyme using MCell 3.3

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By Matthew C Pharris1, Tamara L Kinzer-Ursem1

Purdue University

This model uses a specialized rule-based syntax in MCell 3.3 to model the twelve-subunit CaMKII holoenzyme without inducing combinatorial explosion. The model allows us to explore the regulation of CaMKII activation and autophosphorylation.

Version 2.0 - published on 29 Jul 2019 doi:10.4231/MV0Z-8Z57 - cite this Archived on 29 Aug 2019

Licensed under CC0 1.0 Universal

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