In vitro Volumetric Particle Velocimetry, Computational Fluid Dynamics (CFD), and in vivo 4D Flow MRI Hemodynamic Data in Two Patient-Specific Cerebral Aneurysms

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By Melissa Brindise1, Sean Rothenberger1, Benjamin Dickerhoff2, Susanne Schnell3, Michael Markl3, David Saloner4, Vitaliy Rayz1, Pavlos Vlachos1

1. Purdue University 2. Marquette University 3. Northwestern University 4. University of California San Francisco

Data from a pulsatile volumetric particle velocimetry study using two patient-specific cerebral aneurysm models, processed using Shake the Box (STB). Associated in vivo MRI and CFD datasets are also provided.

Version 1.0 - published on 23 Aug 2019 doi:10.4231/M5F1-QC84 - cite this Content may change until committed to the archive on 23 Sep 2019

Licensed under CC0 1.0 Universal


The data provided in this publication was used to evaluate parameters including wall shear stress (WSS), oscillatory shear index (OSI), and relative residence times (RRT) across multiple modalities and two patient-specific aneurysm geometries. Specifically, the assumptions and limitations of each modality coupled with the varying and often low spatial resolution and their subsequent effect on the hemodynamic metrics was explored. The results of this study demonstrated that non-dimensional parameters, such as OSI, were more robust to varying modalities and spatial resolutions and thus may provide more robust risk or growth and rupture assessments. These results demonstrate a need for further investigation and development of non-dimensional parameters and correlation of such parameters to risk of aneurysm.

Additionally, the pulsatile particle velocimetry results provided here can be used as robust validation test cases for computational fluid dynamics (CFD) solvers.

These data files were created using Matlab 2016.

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