We created a population-specific brain atlas that targets adolescent collision-sport (American football, soccer) athletes, based on the T1-weighted magnetic resonance (MR) images from the longitudinal database of Purdue Neurotrauma Group. The atlas was developed in an effort to minimize bias introduced in image processing, improve statistical power, and therefore better identify and investigate the mechanisms that lead to traumatic brain injury in adolescent athletes, which is one of our long-term commitments to this vulnerable population. Image processing software, including FSL and ANTS, were used to create the brain atlas. To scale and speed up the atlas creation, we established a high-throughput high-performance computing workflow which integrated Open Science Grid and Purdue Community Clusters. In principle, the atlas can be applied in image registration and spatial normalization for MR neuroimaging studies that target adolescent collision-sport athletes.
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Researchers should cite this work as follows:
- Zou, Y., Zhu, W., Yang, H., Talavage, T. M., Rispoli, J. V. (2019). T1-weighted brain atlas for adolescent collision-sport athletes in Purdue Neurotrauma Group longitudinal database. Purdue University Research Repository. doi:10.4231/4668-DM62