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Blue light-induced retinal degeneration in Drosophila melanogaster: Supporting data for Chen et al.

Listed in Series/Dataset publication by group The Weake lab

By Xinping Chen1, Walter Daniel Leon-Salas, Hana Hall1, Jeffrey P Simpson2, Donald F Ready, Vikki Marie Weake3

1. Purdue University 2. Purdue 3. College of Agriculture

Cytochrome-b5 protects photoreceptors from blue light-induced lipid peroxidation and retinal degeneration. Supporting data for Chen et al. HardwareX and NPJ Aging and Mechanisms of Disease articles are provided.

Version 1.0 - published on 08 Nov 2017 doi:10.4231/R789141Q - cite this Archived on 09 Dec 2017

Licensed under CC0 1.0 Universal

BlueDay1Retina.jpg BlueLightDevice.jpg

Description

This data series contains all the raw data and supporting material for the following two publications:

Chen, X., Leon-Salas, W.D., Zigon, T., Ready, D.F. and Weake, V.M. (2017). A programmable optical stimulator for the Drosophila eye. HardwareX 2: 13-33.

Chen, X., Hall, H., Simpson, J. P., Leon-Salas, W. D., Ready, D. F., & Weake, V. M. (2017). Cytochrome b5 protects photoreceptors from light stress-induced lipid peroxidation and retinal degeneration. NPJ Aging and Mechanisms of Disease, 3(1). doi:10.1038/s41514-017-0019-6.

This includes the hardware and software files necessary to build the optical stimulator used to subject the flies to blue light stress, and the results (microscopy, biological assays) supporting the mechanism involved in blue light-induced retinal degeneration.

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Notes

Supporting and raw data are provided for the associated cited studies separated by Figures and/or publications. Supporting data for each figure in Chen et al. studies are published as individual data sets. Information on how to access any specialized file formats are provided in the specific data set. Keys for file names are provided as text files in most figure folders, and describe genotypes/ages/treatments and other experimental variables. For full details of any given experiment, please refer to the published studies (see cited material).

 

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