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Position of MLL1 morphemes in human genomic DNA

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By Minou Bina1, Phillip J. Wyss1, Daidong Wang1, Noorfatin J. Zulkefl1, Elise Novorolsky1

Purdue University, Department of Chemistry

Supplementary materials for the publication entitled “Discovery of MLL1 binding units, their localization to CpG Islands, and their potential function in mitotic chromatin.” Bina M, Wyss P, et al. BMC Genomics. 14:927 (2013).

Version 1.0 - published on 04 Mar 2014 doi:10.4231/R7H41PBT - cite this Archived on 25 Oct 2016

Licensed under CC0 1.0 Universal

Description

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Mixed Lineage Leukemia 1 (MLL or MLL1) may play a central role in the recruitment of transcription factors to chromatin to regulate the expression of genes associated with !CpG islands. We have previously shown that MLL1 binds specific DNA sequence elements known as morphemes: Bina et. al, BMC Genomics 14:927 (2013)

This publication provides a file (Bina_MLL_morphemes_hg19.bed) to display the position of MLL1 morphemes in the human genome browser at UCSC (hg19). You can obtain a copy of the bed file (txt format) by clicking on download. Alternatively, you can use the link below to view the position of MLL1 morphemes directly on a track in the browser at UCSC. While using the genome browser, select Dense for viewing morpheme positions in genomic DNA. Select pack when zooming to short DNA segments.

Open the position of MLL1 morphemes in hg19 at the UCSC genome browser.

If you use the data in your research, please cite the primary publication by Bina et al., published in BMC Genomics. 2013 Dec 28;14:927.

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