In the human genome, regulatory signals are dispersed in DNA sequences and segments that control gene expression. We have developed a computational model to localize the position of potential regulatory signals in human genomic DNA. In this publication, we offer a bed file displaying the position of potential regulatory signals in the human HOXA locus and hits with statistically significant sequence elements in coding sequences (CDSs) of human genes. When displayed in full-format in the human genome browser at UCSC (built hg17), the position of predicted regulatory signals appears in blue and red. Shown in green is the position of hits with statistically significant sequence elements obtained from CDSs. Examples and details can be obtained from the original publication: Open the HOXA locus genome tract in the UCSC genome browser.
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Researchers should cite this work as follows:
- Bina, M., Wyss, P. J., Shah, S. A., Lazarus, S. A., Ren, W., Szpankowski, W., Crawford, G. E., Park, S. P., Song, X. C. (2013). Predicted regulatory signals in the human HOXA locus: supplemental material for the report: Discovering sequences with potential regulatory characteristics. Purdue University Research Repository. doi:10.4231/D3DZ03214